Presentation

• Tibucef 400 Capsule: Each capsule contains Ceftibuten Dihydrate INN equivalent to Ceftibuten 400 mg.
• Tibucef PFS: Each 5 ml reconstituted suspension contains Ceftibuten Dihydrate INN equivalent to Ceftibuten 90 mg.

Description

Ceftibuten dihydrate is a third-generation semisynthetic cephalosporin antibiotic for oral administration used to treat certain infections caused by bacteria. Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis. Ceftibuten was found to be very stable in the presence of five commonly occurring beta-lactamases of both the chromosomal-mediated (P99, K1) and plasmid-mediated (CARB-2, OXA-1, TEM-1) types.

Therapeutic class: Cephalosporin antibiotic.

 

Prescribing Information